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d Previous cardiovascular disease: The term mixed refers to a population that comprises individuals with and without previous ASCVD

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Fluctuations in ROS levels can influence the function of protein kinases, phosphatases, and various enzymatic proteins, thereby affecting critical processes such as cellular metabolism, gene regulation, and proliferation [25]

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For example, niches may be created by addressing specific unmet needs in certain patient types (e.g., patients who prefer not to inject, or who failed prior lines of GLP-1s), or by addressing specific access issues (e.g., developing a lower-cost option, securing broader payer coverage)