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(2018) found that sertraline causes impaired the steroidogenesis of sex hormones in male rats through the direct inhibition of steroid synthesis and its indirect effects on gene expression, and plasma LH levels and LH/testosterone ratios were significantly increased, potentially triggering compensatory hypogonadism

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& Zhao, J

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G., Tanner, C

Weight loss was similar in patients on CSII, with a mean weight loss of 6.3 kg ( 2