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Histology from treated animals shows smaller adipocytes and reduced fat-pad mass

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K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone

When prescribed, peptide therapy is provided under medical supervision with appropriate patient counseling, follow-up, and monitoring based on the individual treatment plan

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Heard et al