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Journal of Clinical Medicine

GLP-1s (glucagon-like peptide-1 receptor agonists) are medications originally developed to treat type 2 diabetes and now widely prescribed for chronic weight management

Zhang, F., Yin, X., Huang, L

One trial also investigated patients that did not respond to initial loperamide treatment, and found also that IBS-D patients refractory to loperamide had improved stool consistency and abdominal pain with eluxadoline (Brenner et al., 2019)

Metabolic control through the PGC-1 family of transcription coactivators

A 10 percent reduction in body weight is associated with a roughly 26 percent reduction in AHI (Peppard et al., JAMA , 2000)