(4) quantified and showed the durability of this phenomenon in chronic obstructive pulmonary disease (COPD) patients who relocated for 3 weeks from Jerusalem (altitude 800 m, 2500 ft, 13.4 psi, 0.91 ATA) to the Dead Sea (altitude 402 m of air below sea level 15.4 psi, 1.05 ATA)
Future research should focus on addressing key technical bottlenecks in clinical translation, including optimizing targeting specificity, ensuring biosafety, and establishing standardized preparation processes, to accelerate the transition of these innovative technologies from the laboratory to clinical application, providing more comprehensive and reliable information support for clinical decision-making(Table 2)
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