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Retatrutide has been studied in a phase 2 trial involving adults without diabetes but with obesity or preobesity (overweight)
It also reduces cardiovascular risk in heavier people with cardiovascular disease
It's also important to note that not all weight loss drugs are created equal
Patients can see their waist change, their shape improve, and their visceral fat reduce while the number on the scale moves very little
Thus, the most promising uses of motilin receptor agonists are the treatment of gastroparesis or conditions with slow gastric emptying, and ghrelin receptor agonists hold potential for the reduction of nausea and vomiting, and the treatment of constipation
some patients titrate faster or slower based on side effects and weight loss progress
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