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As we await 240-week outcomes data, the interim results of the ESSENCE trial showed that semaglutide 2.4 mg weekly in MASH with F2-F3 fibrosis: 63% achieved steatohepatitis resolution vs 34% with placebo (NNT ~3-4), and 37% improved fibrosis stage vs 22% placebo at 72 weeks
doi:10.1073/pnas.1205227109 44
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