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They had every reason not to go out there and cheer me on. Why Jelly Roll Avoided Using GLP-1 Medications for Weight Loss In his January 2026 cover story for Mens Health , Jelly Roll revealed why he chose not to use GLP-1 medications, including Ozempic, Mounjaro and Wegovy, to help achieve his weight loss goals

Specific GLP-1 receptor agonists (liraglutide, semaglutide, dulaglutide) have demonstrated cardiovascular benefits in clinical trials, including reduced risk of major adverse cardiovascular events

They're signals your care team can respond to thoughtfully

Xie et al., 2020, 2021)

for diabetics reduces the blood glucose level, insulin resistance, general inflammation in the body and oxidative stress, stimulates the ability of the pancreas to produce insulin, reduces risk of diabetic complications, such as nephropathy, cataract, retinopathy and development of heart disease

You might feel sick within hours of eating a meal