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For example, in studies where skin fibroblasts were treated with GHK-Cu, there was increased expression of extracellular matrix genes and antioxidant enzymes

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Dermatol Ther (Heidelb) 15 , 31733193 (2025)

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Our study has important implications for our understanding of enzymatically active and inactive glutaredoxins and could be useful for the design and optimization of artificial glutaredoxins, glutaredoxin-coupled fluorescent redox sensors and transition-state inhibitors

Furthermore, L-carnitine has been shown in some studies to act as a peripheral antagonist to thyroid hormone action