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Before & Afters Results vary

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revealed that the rates of neuropathies leading to first/recurrent amputation within 30 years were higher in patients receiving glimepiride 8 mg/day (N=248) than in patients receiving liraglutide 1.2 mg/day (N=251) or liraglutide 1.8 mg/day (n=247), while they were numerically similar between patients receiving liraglutide 1.2 mg/day and liraglutide 1.8 mg/day

The first several years of that commercial window are consumed by the slow ramp of physician adoption, payer negotiations, and market access challenges

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Network meta-analysis on the effects of finerenone versus SGLT2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus and chronic kidney disease