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In a retrospective study of serum 25(OH)D levels in 648 children with epilepsy in China, the serum 25(OH)D level in children with epilepsy was reduced both before and during ASMs treatment, and the SF was significantly reduced in the group treated with ASMs and receiving vitamin D supplements (120)

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Although melatonin treatment was associated with reduced GLUT1 expression ( Figure 5J ), this did not translate into a functional deficit in glucose uptake, as melatonin-treated cells displayed comparable 2-NBDG uptake to controls ( Figure 5K )