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It can range from mild to life-threatening

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These include nausea (affecting 15-44% of users depending on dose), diarrhea (10-30%), vomiting (7-25%), constipation (6-24%), and abdominal pain or discomfort (approximately 9%)

Depletion of tumor-associated macrophages enhances the anti-tumor effect of docetaxel in a murine epithelial ovarian cancer

the switch involves the autophosphorylation of Src activation loop Y416 by another Src molecule 21