how much weight can you lose tirzepatide with 2.5 mg of Mounjaro? Why are you not losing

Veldhuis JD, Keenan DM, Bailey JN, et al

What is the primary goal of deprescribing

The second induction study FIGARO UC 302 (NCT03259334) enrolled 279 participants using an identical design and demonstrated efficacy for both doses, with 25mg achieving clinical remission in 27.0% versus 12.5% placebo and 75mg achieving 29.5% versus 12.5% placebo, while both doses showed significant benefits across secondary endpoints including endoscopic response, clinical response, and mucosal healing, with inclusion criteria requiring patients aged 1866 years with moderate to severe disease and the studies showing good tolerability with most common adverse events being UC worsening, arthralgia, and nasopharyngitis

360 : 146155 Pettegrew JW, Panchalingam K, Levine J, McClure RJ, Gershon S, Yao JK

Because tirzepatide is used so widely, the most reliable data on tirzepatide and hair loss come from the large weight-loss trials

Adipose tissue, particularly visceral fat, is metabolically active and secretes pro-inflammatory adipokines