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Acknowledgements This work was supported by the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre

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Management and Outcomes of Binge-Eating Disorder

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JAAPA 33:318

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Major Differences to Consider Receptor Activation Retatrutide: GLP-1 + GIP + glucagon Semaglutide: GLP-1 only Expected Weight Loss Retatrutide: Potentially greater reductions Semaglutide: Strong but less dramatic Side-Effect Profile Retatrutide may produce more intense gastrointestinal symptoms early on due to its multi-receptor activation

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