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Ilic et al., 2011b
Physiol Rev 94(4):9911026 Alcntara S, Frisn J, DelRo JA, Soriano E, Barbacid M, Silos-Santiago I (1997) TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death
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Conclusion Whilst B12 supplements from the chemist, containing a very low B12 dosage, might be optimal for everyday use
It readily crosses the blood-brain barrier and is widely used in laboratory and preclinical research as a model compound to investigate delta-wave (slow-wave) sleep induction, stress-axis modulation, neuroprotection, circadian rhythm regulation, and related neurotransmitter pathways in various in vitro and animal model systems
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