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In addition, radiotherapy sensitizers containing variable valence metals can effectively sensitize radiotherapy via oxidation-reduction reactions with GSH
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The nonclassical pathway of pyroptosis is induced by direct stimulation and oligomer formation of caspase 4, caspase 5 (in humans), and caspase 11 (in mice [42]) through the binding of their amino (N)-terminal caspase activation and recruitment domain to the gram-negative bacterial lipopolysaccharide [43])
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