While Semaglutide GLP-1 has proven successful, tirzepatide has shown even better results in clinical trials
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Once-daily treatment with oral semaglutide was initiated and subjects were dose-escalated weekly from 3 to 7 mg, and then from 7 to 14 mg
Five patients discontinued treatment due to lack of efficacy or unwillingness to continue
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And while the drugs safety profile appears to be in line with approved GLP-1 drugs, at least some people discontinued taking retatrutide due to the drugs adverse effects