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copper-coordinated) Sequence GHK Molecular formula C14H24CuN6O4 Molecular weight 403.92 Da CAS 89030-95-5 GHK-Cu: copper peptide signaling and dermatological research The published ghk-cu copper peptide research literature spans more than five decades, beginning with the 1973 isolation of a growth-modulating tripeptide from human plasma by Loren Pickart and continuing through contemporary gene-signature work that has reframed the molecule as a broad transcriptional modulator rather than a single-pathway signal (Pickart & Thaler, 1973