As we age, the brain's ability to form and maintain synaptic connections declines and that loss tracks with the memory and processing changes many people notice over time
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[2] Jeanne JF, Papineni S, Mayfield D, Camillerapp C, Leroux A
N Engl J Med 384(12):11131124 Osaka T, Endo M, Yamakawa M, Inoue S (2005) Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system
It is FDA-approved as Ozempic (2017), Wegovy (2021), and Rybelsus (2019, oral formulation), and serves as the reference compound for the broader class of long-acting GLP-1 receptor agonists
Infect Immun (2004) 72(3):13916