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An encouraging strategy involves the development of small molecule inhibitors or alternative therapeutic agents that directly target FSP1, consequently augmenting the susceptibility of tumor cells to GPX4 inhibitors [252]
Angiogenesis, FAK-paxillin signaling, nitric oxide upregulation
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We hypothesized that the lack of accumulated cysteine and glycine could be due to these metabolites entering alternative metabolic pathways
J Hum Genet 46:289292 James LP, Mayeux PR, Hinson JA (2003) Acetaminophen-induced hepatotoxicity
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