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To test the function mechanism of purified reGSTA2X under different conditions, it was incubated with the addition of divalent metal ions (Fe 2+ , Zn 2+ , Mn 2+ , Cu 2+ , and Mg 2+ ) at the concentration of 1 mmol/L or 0.1% sodium dodecyl sulfonate (SDS)
In peripheral tissues, it helps in -oxidation by transporting medium and long chain fatty acids into the mitochondria [30]
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Through a comprehensive analysis of histone modifications in lesional skin from both psoriasis patients and mice, the significantly increased level of histone acetylation at H4 lysine 16 (H4K16ac) in macrophages was found, which was positively correlated with the accumulation of self-RNA in the dermis and psoriasis pathology
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