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p53-pS15 is involved in regulating cell cycle arrest and apoptosis resistance in keloids Phospho-specific protein microarray was used to investigate the cell signaling profile in fibroblasts from keloid versus those from adjacent skin
13, S272S276
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Similarly, the same mutation in rodents also causes increased ROS in Schwann cells and leads to death of primary Schwann cells in culture
As glutathione levels decline with age, the resulting shift in redox balance may contribute to the pro-inflammatory state documented in aging populations sometimes described in the research literature as "inflammaging." Evidence level: Moderate
