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5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)
Avoid alcohol and caffeine, which can irritate the stomach
Monotherapy versus Combination Therapy The decision to initiate drug therapy with metformin alone or in combination with another agent is influenced by HbA1C level and health status when diabetes is newly diagnosed
PMID 6808975
(PubMed) Millard HR, Musani SK, Dibaba DT, et al
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