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According to the Ozempic Summary of Product Characteristics (SmPC), gastrointestinal adverse effects are common, but a causal relationship with persistent gastroparesis has not been established

Polymorphism of glutathione S-transferase in laboratory rats [PMID: 6670994] Laboratory literature summary: Polymorphism of glutathione S-transferase in laboratory rats

That opportunity is now supported by manufacturing commitments, including Novo Nordisk's March 2026 announcement of a EUR 432 million expansion in Athlone, Ireland, to increase capacity for oral GLP-1 therapies, alongside Eli Lilly's November 2025 plan to build a USD 3 billion manufacturing facility in Katwijk, the Netherlands, aimed at oral medicines including the GLP-1 receptor agonist orforglipron

To examine this hypothesis and evaluate the therapeutic prospects of pharmacological glutathione synthesis inhibition within the native microenvironment of a lymphoma, we treated -Myc mice with BSO