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Ethical approval The study was approved by the Institutional Review Board for Clinical Research Committee (IRB) of Mansoura University with the approval code R.22.10.1897.R1 and with the IRB committee, Al Yousif Hospital, Alkhobar, Saudi Arabia, (AYH IRB: 02/03/2023)

Understanding how much water you need daily on GLP-1 therapy helps prevent complications, minimize discomfort, and support your weight management or diabetes goals

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Start tirzepatide on your next scheduled injection day

It is possible that serious reactions which will require immediate medical attention may occur

Negative control was incubated with water instead of Tdt