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GLP-1 slows gastric emptying, which can delay or reduce absorption of oral supplements

Placebo-controlled superiority trials in type 2 diabetes (T2D) LEADER, SUSTAIN-6, REWIND, and SOUL and in obesity without diabetes (SELECT) demonstrated statistically significant reductions in major adverse cardiovascular events (MACE) of approximately 12%26% [3], [4], [10][12]

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Communication between perioperative teams and prescribing clinicians is particularly important when medication interruption is being considered, as discontinuation may require individualized management plans to maintain glycemic control and therapeutic effectiveness