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Methylfolate helps power the methylation cycle, which regulates: Homocysteine metabolism Neurotransmitter production (serotonin, dopamine, norepinephrine) Hormone regulation Detoxification and antioxidant production DNA synthesis and repair When the MTHFR gene has a variant (like C677T or A1298C), the enzyme works less efficiently

The liposome acts like a delivery vehicle, allowing the nutrient to bypass traditional digestion and be absorbed directly into the bloodstream or even the cells

Xenograft study GBM cells (5 10 5 ) suspended in 5 l of DMEM were intracranially injected into female 4-week-old athymic nude mice (five mice/group) obtained from GemPharmatech (Nanjing, China)

O'Donnell, V

While found throughout the body, its more prominent in the liver and in fat cells

Cancer Res 2009