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National peak body Exercise and Sports Science Australia also warned that Australias unregulated GLP-1 weight-loss medication boom was leaving patients muscle-depleted and in danger of premature frailty. ESSA said research shows that 15 per cent to 40 per cent of weight lost during treatment may come from lean tissue, including skeletal muscle. Australias Minister for Health Mark Butler has also backed a cautious, staged rollout of subsidised GLP1 treatments

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