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Fibrillar structures were also observed, but they were not associated with copper ions, suggesting that copper promotes the formation of toxic oligomers that disrupt membranes ( Impaired autophagy plays an important role in IAPP toxicity, due to the accumulation of excessive amounts of IAPP oligomers intracellularly
& Anders, S
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Statistical analysis All values were expressed as Mean standard error of the mean (SEM)
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The research rationale for studying the two together is mechanistic complementarity
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