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doi: 10.2337/dc24-S009 14 DruckerDJ
Commonly reported weight loss methods were exercising and consuming less food, followed by increased fruit, vegetable, and salad consumption
The decrease in S100a8, S100a9, and Cxcl2 levels suppress inflammation and oxidative stress in cardiac muscle, thereby reducing the risk of myocardial infarction, heart failure, arteriosclerosis, and myocardial reperfusion injury
286 The landmark SELECT trial has demonstrated the cardiovascular benefits of the GLP-1 receptor agonist, semaglutide (2.4 mg subcutaneous once weekly), in people established atherosclerotic CVD and with a BMI 27 kg/m2 (without type 2 diabetes)
Gastrointestinal events occurred at 3%7% incidence with ALA and curcumin, but no trial was powered to rule out rare but clinically relevant toxicities