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Higher cardiorespiratory fitness means lower risk of metabolic syndrome, diabetes, dementia, and death from any cause
Because retatrutide does not currently hold regulatory approval in the UK, there are no formal prescribing eligibility criteria in the way that exist for licensed medicines
Maintenance phase includes partial meal replacements only for the first 4 weeks, supplemented by regular meals
The combination could theoretically protect against the muscle wasting that sometimes accompanies aggressive caloric restriction
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