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Weight loss with Zepbound can begin within the first four weeks of treatment, while weight loss with Trulicity may take several months to become noticeable

Tirzepatide generally shows greater average weight reduction, while semaglutide has a longer clinical history and more extensive real-world use data

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To mitigate this issue, more studies should be published over time to ensure a more representative sample of research findings

For instance, Farnesoid X-receptor (FXR) activation leads to the suppression of the cholesterol 7a-hydroxylase enzyme