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It's a current state of action

Although taking these meds doesnt automatically equal deficiency, your doctor should keep an eye on your B12 levels, especially if youve been taking acid-blockers for longer than a year or metformin for more than four months, according to an article in the journal, American Family Physician (9)

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That dampened craving is part of the appetite effect doing its job, and leaning into it rather than fighting it makes the whole run smoother

These fall under a different regulatory category, and their safety and quality controls vary dramatically