Data on dermal toxicity caused by copper compounds is scant
Excretion and clearance As a small peptide (15 amino acids, approximately 1419 Da), BPC-157 is likely cleared primarily through proteolytic degradation and subsequent clearance of amino acids and small fragments, rather than significant excretion of intact peptide
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IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes
The formulations uniqueness lies in delivering synergistic quantities of methyl-donor amino acids (methionine and choline), a carnitine shuttle cofactor, and a provitamin B derivative in one injection, thereby bypassing gastrointestinal absorption limits that may hinder oral supplementation
Research references 10 mcg/kg in animals, and human practice typically uses 200 to 800 mcg per day