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Phase 2 retatrutide trials reported higher average weight loss than published outcomes for either tirzepatide or semaglutide at comparable durations, though direct head-to-head trials have not yet been published
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Prog Neurobiol 92(3):442462 Vrang N, Phifer CB, Corkern MM, Berthoud H-R (2003) Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons
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Although Glp1r mRNA transcripts are detected in whole heart extracts such methods do not distinguish between vascular smooth muscle cells or atrial cardiomyocytes, there were technical difficulties in isolating pure cardiomyocyte populations from the ventricle without contamination of atrial cardiomyocytes isolated from neonatal mouse [36]
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