Occasional injection site irritation or digestive changes may occur early in use
T ransient nausea, diarrhea, and mild irritation at the injection site have been reported as adverse undesirable effects in preclinical studies
Ppar Hippo mice that harbor conditional Ppar deletion in the hippocampal neuronal cells were generated by breeding Ppar flox mice (46) with B6.Cg-Tg (Camk2a-Cre) T29-1Stl/J mice expressing Cre recombinase under the guidance of the calcium/calmodulin-dependent protein kinase II (Camk2a) promoter (obtained from The Jackson Laboratory)
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