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Eight weeks of aerobic exercise significantly activated the System Xc /GPx4 signaling pathway in the prefrontal cortex of APPswe/PS1dE9 transgenic AD mice, up-regulated FTL and BACE1 expression, significantly downregulated 4-HNE levels, inhibited oxidative stress, lipid peroxidation, and ferroptosis, reduced A positivity, alleviated neuronal morphological abnormalities, and improved learning and memory functions in AD mice (Li et al., 2024a)
Sato Y., Harada K., Kizawa K., Sanzen T., Furubo S., Yasoshima M., Ozaki S., Ishibashi M., Nakanuma Y
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Reason 4: Cost-benefit mismatch
Our Dihexa peptide is provided at high purity standards to support consistent research results
