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As the CF population ages, however, age-related components are expected to become even more prevalent, including CF-related diabetes (CFRD) where rates are approaching 100% in individuals with common severe CFTR mutations 3
As of March 2026, two trials are actively recruiting new participants: the Maintenance trial (NCT06859268, testing dose reduction after initial weight loss) and a new enrollment trial (NCT07232719, 250 participants with obesity or overweight)
Recent research has revealed that GLP-1 receptor agonists have potent anti-inflammatory properties that extend well beyond their metabolic effects, targeting different pathways in different tissues and demonstrating a broad spectrum of actions
Hemodynamic stabilizing effects of L-carnitine in chronic hemodialysis research subjects [PMID: 24454315] Laboratory literature summary: Hemodynamic stabilizing effects of L-carnitine in chronic hemodialysis research subjects
For those who may be worried about affording the name-brand GLP-1 medications, Ewing said it is always worthwhile to check with your insurance provider about their coverage for weight-loss medications, as formularies can change, and what was not covered before might be now
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