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The AKT pathway can phosphorylate more than fifty substrate proteins and modulate processes disrupted in PD, such as the enhancement of synapse formation, autophagy, and LTP, as well as inhibiting the secretion of pro-inflammatory cytokines, apoptosis, microglial activation, tau phosphorylation and the accumulation of -synuclein and A (Fig

Mejora la apariencia de la piel de naranja

Lster H, Miehe K, Punzel M, et al

The number of layers was reduced, and cell polarity disappeared

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This study was approved by the Ethics Committee of the Heidelberg University (S-269/2015)