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Sun Y et al
Timing them separately is fine
Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis
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When microphthalmia-associated transcription factor (MITF) is bound by active CREB, it triggers the transcription of melanogenic enzymes [12, 122, 191]
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