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some may respond within 15 minutes at higher doses [9] These medications work by enhancing nitric oxide-mediated relaxation of penile smooth muscle, facilitating increased blood flow during sexual stimulation
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PT-141 is taken 45 to 60 minutes before sexual activity
This makes oral administration a viable primary route with the arginate form, not just a convenience compromise
"Clinicians should clearly distinguish biological plausibility, animal research, and anecdotal reports from demonstrated benefit in well-conducted human trials
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