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Multi-agonist peptides that incorporate AMY receptor agonism have also been developed as illustrated by PTT-A, a long-acting tetra-agonist at the GLP-1, GIP, amylin and calcitonin receptors that decreased food intake and body weight in a rat model of obesity [71]
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It is often described as a triple-agonist due to its activity on GLP-1, GIP, and glucagon receptors
K., Christiansen, E., Hertz, C
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