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Epub 2018 Apr 16
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In addition to downregulation of GCLC, we found increased expression of glutaredoxin GLRX5 and a very small, but significant, increase in GGT1 expression in tumors compared to nontumor tissues (Fig 2B and D)
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CagriSema, at least in its current clinical development program, targets a single maintenance dose of 2.4/2.4 mg, offering less room for individualization
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