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Research using MC4R knockout mice and selective MC4R antagonists has established MC4R as the primary receptor mediating MT-IIs pro-erectile and pro-sexual effects with MC4R-null mice showing substantially reduced or absent MT-II-induced erections and sexual behaviour, and MC4R-selective antagonists blocking these responses at doses not affecting MT-IIs melanogenic activity

(2018) 20 Suppl 1:521

Side Effects & Mitigation GLOWs side-effect profile is driven mainly by its components known reactions in research settings

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