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This was suggested to be accompanied by decreased transcription of urea cycle enzymes, restoration of nitrogen balance, and possible redistribution of nitrogen stores across organs
Moreover, inflammatory factors induced by high salt intake can shift the tumor microenvironment towards a pro-inflammatory state, which may inhibit tumor progression
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At 15 weeks of age, before the termination the mice were fasted for 2 hours followed by intraperitoneal injection of 80 mg/kg ketamine and 10 mg/kg xylazine to proceed for the dissection
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