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AOD-9604 is unlikely to interact with most medications because its mechanism is confined to adipocyte lipolysis and it does not bind plasma proteins at significant levels

Cortisol, on the other hand, is a hormone produced by the adrenal glands in response to stress

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developed a biomimetic nanomodulator targeting sepsis-associated encephalopathy, which crossed the blood-brain barrier, alleviated oxidative stress, polarized macrophages toward anti-inflammatory phenotypes, and improved cognition and survival (Qu et al., 2024)

We confirmed that this study was carried out in compliance with the ARRIVE guidelines

doi: 10.1089/omi.2011.0118