Kerstholt, M., Vrijmoeth, H., Lachmandas, E., Oosting, M., Lupse, M., Flonta, M., Dinarello, C
Primary Handling Editors: Jin-Min Nam and Tobias Goris
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Betegon M, Brodsky JL
Research Applications Investigation of melanocortin receptor signaling pathways Study of peptidereceptor binding affinity and interaction dynamics Analysis of intracellular signaling processes related to -MSH analog peptides Use in biochemical research models involving melanocortin-based signaling systems Key Features High-purity lyophilized research peptide (99%) Synthetic -MSH analog with linear peptide structure Stable molecular profile suitable for controlled laboratory research Designed for precise biochemical and receptor signaling studies Content Compound: Melanotan I (Afamelanotide) Form: Lyophilized powder Storage Information Store in a cool, dry place protected from light Refrigeration recommended for maximum stability Use within the recommended timeframe after reconstitution Research Use Only

Glutathione (GSH) enhancement in a concentration-dependent manner (millimolar concentrations) in DC is directly associated with IL-12 production, which in turn favours a Th1 CD4+ T cell response, resulting in the production of IL-2, IL-12, and IFN-