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Long-term use of GLP-1 receptor agonists like Ozempic has been associated with an increased risk of vitamin B12 deficiency
This establishes the peptide as a potent agent within the central and peripheral nervous systems, capable of modulating key neurotransmitter systems and facilitating recovery from injury
When Surgical Delay Is Not Negotiable If the B12 deficiency is severe (particularly if below 100 pmol/L or with neurological symptoms), I do not proceed, regardless of the patients preferences regarding timing
Alternatives: Are there better-established options for what I am trying to achieve
Shannon offers the summary below: The preclinical science is genuinely exciting and promising for regenerative medicine
while the acute repletion might be IV/IM for a period, they may transition to high-dose oral vitamins thereafter
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