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For doses over 1.5 mL, split into two sites injected simultaneously or within 5 minutes
Os medicamentos agonistas do receptor de GLP-1, indicados principalmente para tratamento da obesidade e do diabetes tipo 2, reduzem o apetite, aumentam a sensao de saciedade e alteram significativamente a relao de muitos consumidores com a alimentao
Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)
9,50 A phase 3 trial is not yet registered but is anticipated to commence soon
Combining both creates a comprehensive strategy for long-term vitality and confidence
References: Pickart et al
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