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These findings have also been described for MDD, e.g., in a large meta-analysis by Bot and Milaneschi et al., which found an association between depression risk and different lipid classes [14] and in several other studies, as reviewed in detail by Guerreiro Costa et al
While these results are striking, important variables like pharmacokinetics, metabolism, and receptor sensitivity differ significantly between mice and humans
Due to the fact that ACTL6A did not regulate NRF2, we could reach the conclusion that ACTL6A functions in conjunction with NRF2 to regulate GCLC expression at the transcriptional level
Glutathione neutralises free radicals by donating electrons to convert them into stable, harmless forms
Liquid chromatography separates compounds in a sample before mass spectrometry analysis
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